Enabling development of new medicines for challenging diseases

Vision

We unlock the potential of Macrocycles to create tomorrow’s breakthrough drugs. These unique small molecules interact with novel biological targets, offering untapped therapeutic potential and the possibility of oral bioavailability.

Mission

Our mission to accelerate the discovery of novel therapeutics by leveraging cutting-edge computational algorithms, a highly efficient wet lab workflow, and sustainable research practices. Through high-throughput experimentation, machine learning, and green chemistry, we generate and validate vast libraries of Macrocyclic compounds with biological relevance and optimized ADME properties.

Laboratory setting with molecular model, glassware, and laptop on a reflective surface.

“With a focus on macrocycles, molecular glues, and diversity libraries, we offer a range of compound library services for targeting challenging drug targets.”

Anna Rzepiela – CEO Pyxis Discovery

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Featured success story: Scientific Publication.
Our recent paper published in the Journal of Medicinal Chemistry, marks a promising advancement in understanding how synthetic Macrocycles can be optimized for drug design. By studying how the 3D structure and flexibility of these molecules influence their ability to cross cell membranes, we have reported on valuable insights that can help make Macrocycles more effective in targeting challenging disease-related proteins.

Read success story

A close-up of a molecular model beside a laptop displaying molecular structures and data, emphasizing scientific research.

Work at Pyxis?

By joining Pyxis you will have the opportunity to get involved in a wide variety of life science projects, while being given the responsibility to shape and drive the future of our company along with your own career track.

We are looking for talented individuals who will contribute to our continuing success through their unique expertise, passion and dedication.

Interested? Send an email to info@pyxis-discovery.com